Omepral | Omeprazole Review, Uses, Effects and Side Effects

Omepral is use to treat symptoms of reflux esophagitis or reflux disease. This can be cause by “washing back” of food and acid from stomach into food pipe. Omepral also take to help stop reflux esophagitis coming back or relapsing. In this page we talk about Omepral | Omeprazole Review, Uses, Effects and Side Effects.




Omepral is type of medicine call proton pump inhibitor. It works by decreasing amount of acid made by stomach. It give relief of symptoms and allow healing to take place. Omeprazole patent in 1978 and approve for medical use in 1988. It is also available without prescription in United States.

Omeprazole is use to treat certain stomach and esophagus problems such as acid reflux and ulcers. It works by decreasing amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing and persistent cough. This medication helps heal acid damage to stomach and esophagus. It helps prevent ulcers and may help prevent cancer of esophagus.

Omeprazole belongs to class of drugs known as proton pump inhibitors. If you are self treating with this medication, over counter Omepral products are use to treat frequent heartburn. Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away.

For over counter products, carefully read package instructions to make sure product right for you. Check ingredients on label even if you have use product before. The manufacturer may have change ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking wrong product could harm you.

Omepral Effects:

Omepral Effects

This leaflet answers some of common questions people ask about Omepral. It does not contain all information that is known about Omepral. It does not take place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor will have weighed the risks of you taking Omepral against benefits they expect it will have for you. If you have any concerns about taking this medicine ask your doctor or pharmacist. Keep this leaflet with the medicine. You may need to read it again.

  • Omepral is use to treat symptoms of reflux oesophagitis or reflux disease. This can be cause by reflux of food and acid from stomach into oesophagus.
  • Omepral is use to treat peptic ulcers.
  • Depending on position of ulcer it is call gastric or duodenal ulcer. A gastric ulcer occurs in stomach. A duodenal ulcer occurs in duodenum which is tube leading out from stomach.
  • Omepral is also use to help stop gastric or duodenal ulcers coming back.
  • Most people who have peptic ulcer also have bacterium call Helicobacter pylori in their stomach.
  • When Omepral is take with antibiotics, they work to kill bacterium and your ulcer heal. 
  • Some peptic ulcers are cause by taking medicines call non steroidal anti inflammatory. Also drugs type of medicine use to treat pain or inflammation.
  • Omepral is also use to heal and prevent ulcers associate with NSAIDs.
  • The Omepral is also use to treat rare condition called Zollinger Ellison syndrome.

Omepral Side Effects:

Omepral Side Effects

Omeprazole is safe medicine and most children can take without having any side effects. Occasionally, OMEPRAL may be associate with changes in your liver or blood. It may require your doctor to do certain blood tests.

These are very serious side effects. You may need urgent medical attention or hospitalization. These side effects are may be rare. All medicines can have side effects. Sometimes they are serious, most of  time they are not.

You may need medical treatment if you get some of side effects.

  • Constipation
  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Skin rash
  • Dizziness
  • Dry or sore mouth
  • Muscle pain
  • Weakness or joint pain
  • Pins and needles
  • Changes in sleep patterns
  • Mood changes, confusion or depression
  • Blurred vision
  • Fever
  • Increase bruising
  • Increase sweating
  • Hair loss
  • Tremor
  • Swelling of face
  • Shortness of breath or difficulty in breathing
  • Skin reaction 
  • Ulcers, blisters or bleeding of lips, eyes, mouth, nose and genitals
  • Swelling of hands, feet or ankles
  • Yellowing of skin or eyes
  • You begin to vomit blood or food

Omepral Dosage:

Tablets should be swallow whole with glass of water or juice. Your child should not chew tablet. Tablets should not be crush.

Capsules should be swallow with glass of water or juice. Your child should not chew capsule. You can open capsule and mix contents with small amount of soft food such as yogurt, honey or jam. Make sure your child swallows it all straight away without chewing granules.

                 AGE                DOSAGE                 TIME
Adults 12 years  40 mg 24 hours
6 to 12 years 20 mg 24 hours
4 to 6 years 10 mg 24 hours
Up to 1 year Do not use it. Do not use it.

Liquid omeprazole:

Liquid omeprazole can prescribe by doctor and made to order for children. People who cannot swallow capsules or tablets.

Measure out right amount using an oral syringe or medicine spoon. You can get from your pharmacist. Do not use kitchen teaspoon as it will not give right amount. Make sure your child takes it all straight away.

It come with syringe or spoon to help you take right amount. If you do not have syringe or spoon, ask your pharmacist. Do not use kitchen teaspoon as it will not give right amount.

Tablets and capsules:

Tablets and capsules

Each tablet or capsule contains 10mg, 20mg or 40mg of omeprazole. Swallow tablets and capsules whole with a glass of water or juice.

If you have problems swallowing capsules, you can open some brands of omeprazole capsules and mix granules. Inside with a small amount of water or fruit juice or sprinkle them on soft food. Such as yogurt or apple puree.

Do not open capsules that have a special coating. Talk to your pharmacist if you are not sure whether you can open your capsules.

Omeprazole also comes as a tablet that melts in your mouth. You can buy omeprazole 10mg tablets and capsules from pharmacies.

They are same as omeprazole 10mg tablets and capsules that you get on prescription. But they mean to be take only by adults, and only for up to 4 weeks.

How Omepral Works?

How Omepral Works?

OMEPRAL works by decreasing amount of acid made by stomach. To give relief of symptoms and allow healing to take place. This does not stop food being digest in normal way.

Follow all directions given to you by your doctor carefully. They may differ from information contain in this leaflet. Ask your doctor if you have any questions about why this medicine has been prescribe for you. Your doctor may prescribe this medicine for another reason.

There is no evidence that Omepral is addictive. This medicine is only available on prescription. Omepral tablets are pink, oblong shape, mark with 20 mg on one side and logo on other side.

Omepral Ingredients:

Omepral Ingredients

Each Omperal tablet contains omeprazole magnesium as active ingredient equivalent to omeprazole 20 mg. If your doctor tells you to stop taking OMEPRAL or tablets have pass their expiry date. Ask your pharmacist what to do with any tablets you have left over.

Here us the Plus following inactive ingredients:

  • Glycerol monostearate
  • Hyprolose
  • Hypromellose
  • Magnesium stearate
  • Methacrylic acid copolymer
  • Microcrystalline cellulose
  • Synthetic paraffin
  • Macrogol 6000
  • Polysorbate 80
  • Crospovidone
  • Sodium stearylfumarate
  • Purified talc
  • Titanium dioxide
  • Triethyl citrate
  • Sodium hydroxide
  • Sugar spheres 
  • Iron oxide red

Omepral Tablets are available in blister packs of 30 tablets. OMEPRAL tablets do not contain gluten. The OMEPRAL® is register trademark of AstraZeneca group of companies.

How to keep Omepral?

  1. Keep your Omepral in blister pack until it is time to take them.
  2. If you take Omepral out of blister pack they will not keep well.
  3. Keep it in cool, dry place where temperature stays below 25°C.
  4. Do not store it or any other medicine in bathroom or near a sink.
  5. Do not leave it on a window sill or in car.
  6. Heat and dampness can destroy some medicines.
  7. Keep it where young children cannot reach it.
  8. A lock cupboard at least one and half metres above ground is good place to store medicines.

Cautions with other medicines:

Cautions with other medicines

Some medicines and omeprazole can affect each other and make it more likely that you will have side effects.

Tell your doctor if you’re taking these medicines before you start omeprazole treatment:

  • Heart medicines such as digoxin
  • Cilostazol treats peripheral arterial disease
  • Antifungal medicines such as itraconazole, posaconazole and voriconazole
  • Methotrexate treats psoriasis and rheumatoid arthritis
  • HIV medicines
  • Phenytoin
  • Rifampicin
  • Blood thinning medicines such as clopidogrel and warfarin

These are not all medicines that may not mix well with omeprazole. For full list, see leaflet inside your medicine packet.

What other information should I know?

Keep all appointments with your doctor and laboratory. Your doctor may order certain laboratory tests before and during your treatment especially if you have severe diarrhea. Before having any laboratory test tell your doctor and laboratory personnel that you are taking omeprazole.

Do not let anyone else take your medication. If you are taking prescription omeprazole, ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep written list of all of prescription and nonprescription medicines you are taking. As well as any products such as vitamins, minerals or other dietary supplements.

You should bring this list with you each time you visit doctor or if you are admit to hospital. It is also important information to carry with you in case of emergencies.



If your doctor has direct you to use this prescription medication. Your doctor or pharmacist may already be aware of any possible drug interactions, health risks and side effects.

They may be monitoring you for them. Do not start, stop or change dosage of this drug or any medicine. Before checking with your doctor, health care provider or pharmacist first. Severe Interactions of omeprazole include:

  • Erlotinib
  • Nelfinavir
  • Rilpivirine

Omeprazole has serious interactions with at least 22 different drugs. Omepral has moderate interactions with at least 75 different drugs. Omeprazole has minor interactions with at least 52 different drugs.

This document does not contain all possible interactions. Therefore before using this product, tell your doctor or pharmacist of all products you use. Keep list of all your medications with you and share list with your doctor and pharmacist. Check with your doctor if you have health questions or concerns.

When should Omepral be not use?

Allergic to Omepral and Substitute Benzimidazoles:

This medicine should not be use in patients with known allergic reaction to it. These patients may have following symptoms if they use this medicine:

  • Life threatening allergic reaction
  • Swelling of lower layer of skin
  • Tightening of smooth muscles of lungs 
  • Swelling in between kidney tubules
  • Hives

Traveling With Medication:

Traveling With Medication

  • Ensure that you carry enough doses of each of your prescription medicines to last entire trip. The best place to store your medicines is in carry on baggage.
  • However, while flying if carrying liquid medicines make sure you do not go over limits imposed for carry on liquids.
  • While traveling overseas make sure that you can carry each of your prescription medicines legally to your destination country.
  • One way to ensure this is by checking with your destination country’s embassy or website.
  • Make sure that you carry each of your medicines in their original packaging.
  • It should typically include your name, address and details of prescribing doctor.
  • If your travel involves crossing time zones.
  • You are require to take your medicine as per fix schedule.
  • Make sure that you adjust for change in time.

Expire Medication:

Taking single dose of expire Omepral is unlikely to cause side effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expire medicine may become ineffective in treating your prescribe conditions.

To be on safe side, it is important not to use an expire drug. You are much safer by always keeping fresh supply of unexpire medicines.

Safe Disposal of Medication:

Safe Disposal of Medication

  • If there are disposal instructions on package, please follow instructions.
  • If there are medicine take back programs in your country. You should contact respective authority to arrange for disposal of medicine.
  • The Drug Enforcement Administration regularly hosts National Prescription Drug Take Back events.
  • If there are no take back programs mix medicine with dirt and place them in seal plastic bag.
  • Throw plastic bag in your household trash.
  • Separately, remove all personal information including prescription label from medicine packaging and then dispose off container.
  • If specifically indicated on medicine package. That it needs to be flushed down toilet when no longer needed perform require step.

Common Causes of Digestive Diseases:

The following are most common causes of Digestive Diseases:
  • Gastrointestinal motility problems
  • Excessive acid production
  • Use of non-steroidal anti inflammatory drugs
  • Cigarette smoking

Other Causes of Digestive Diseases:

Other Causes of Digestive Diseases

The following are less common causes of Digestive Diseases:

  • Smoking
  • Diarrhea
  • Constipation
  • Muscle damage
  • Weakness
  • Nerve damage
  • Loss of stretch in rectum
  • Childbirth by vaginal delivery
  • Hemorrhoids
  • Rectal prolapse
  • Rectocele
  • Swallow air
  • Fiber
  • Obesity
  • Lack of exercise

Risk Factors for Digestive Diseases:

The following factors may increase likelihood of Digestive Diseases:

  • Recent foreign travel
  • Contact with symptomatic persons
  • Contact with a dog with diarrhea
  • Consumption of products containing formula milk
  • Prior diagnosis of several types of atopic diseases

Prevention of Digestive Diseases:

Yes, it may be possible to prevent Digestive Diseases. Prevention may be possible by doing following:

  • Use only purified or bottled water for drinking.
  • Kindly use boiled tap water.
  • Eat fully cooked and hot food.
  • Do not eat un-wash or un-peel raw vegetables and fruits.



The long term use of this medicine may lead to decrease in absorption of vitamin B12. These patients are at increase risk when using this medicine. The use of proton pump inhibitors with methotrexate may increase level of methotrexate in blood. Patients should temporarily stop use of proton pump inhibitors during intake of high dose of methotrexate.

Such patients are at increase risk when using this medicine. Omepral causes increase in chromogranin A protein levels in blood that lead to false. Positive results for abnormal growth of cells of endocrine and nervous system. It is advise to stop Omepral treatment temporarily before examining CGA levels. In case if initial levels of CGA are high then test should be repeat.

Patients using antidepressants and antibacterial drugs are at increase risk when using this medicine. In such patients, levels of Omepral is decrease. These patients are at increase risk when using this medicine. Such patients may suffer from severe side effects like heart palpitation, seizures and uncontrolled contractions of muscles. Careful monitoring of magnesium levels is require before initiating treatment.

These patients are at increase risk when using this medicine. Omepral prevents antiplatelet effect of clopidogrel. These patients should not take Omepral and clopidogrel together. Patients using this medicine are increase risk for developing weak bone related fractures of  wrist or spine. Low dose should given to these patients for shorter duration. Patients using this medicine are at increase risk of developing Clostridium difficile associated diarrhea. Low dose should be give these patients for shorter duration.

Such patients are at increase risk of developing stomach cancer when using this medicine. Treatment with Omepral does not prevent presence of stomach ulcers in these patients.


Omepral has generic name omeprazole. It decreases amount of acid produced in stomach. It is use to treat duodenal and gastric ulcer disease, gastroesophageal reflux disease and Zollinger Ellison syndrome and hypersecretory condition. Omepral is type of medicine call proton pump inhibitor. Omeprazole belongs to class of drugs known as proton pump inhibitors. Omepral is use to treat symptoms of reflux oesophagitis or reflux disease.


What is Omepral tablets use for?
OMEPRAL is use to treat symptoms of reflux oesophagitis or reflux disease. This can be cause by reflux of food and acid from stomach into food pipe. Reflux can cause burning sensation in chest rising up to throat also known as heartburn.
Can you take omeprazole after food?
Take omepral capsules or delay release capsules before meal, preferably in morning. Omeprazole tablets may be take with food or on empty stomach. Take omeprazole powder for oral suspension on empty stomach at least 1 hour before meal.
Why is omeprazole bad?
Common Omepral side effects include headache, stomach pain and nausea. Long term Prilosec use has been link to kidney damage, bone fractures and other dangerous side effects.

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